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DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg Abdul-Hadi

SKU 81542005361
4.4
EUR345.00 EUR386.00

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Description

Abdul-Hadi

NCCNC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(O)C=C1OC1=C3C=CC(O)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

a highly potent topoisomerase I inhibitor derived from camptothecin

613 SMILES NCCCCCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg Abdul-HadiSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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