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Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Carmichael

SKU 70720177366
4.3
USD445.00 USD493.00

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Ships within 48 hours · Estimated delivery Aug 19 - Aug 24

Description

Carmichael

Product Name Lenalidomide-acetamido-O-PEG3-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-PEG3-C2-Cl CAS Number n/a Related CAS Molecular Formula C23H30ClN3O8 Molecular Weight 511

Product Name Lenalidomide-5'-CO-C3-alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg CarmichaelSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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