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the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes
Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C94H155N13O29 Molecular Weight 1931
Product Name Azide-Dap(m-PEG4)-Val-Cit-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C38H54N10O14 Molecular Weight 874
415 Purity (HPLC) >= 95% Solubility DMSO
Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-PNP protac precursor the labeling efficiency of tetramethylrhodamineSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine
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