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1038/s41589-020-0594-x
where they serve as highly potent cytotoxic payloads
Product Name 3-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}propanoic acid Synonyms CAS Number 242459-97-8 Related CAS Molecular Formula C12H22N2O4 Molecular Weight 258
Product Name CP-SS-SulfoCy5 Synonyms SNAP2-SS-SulfoCynine 5 CAS Number Related CAS Molecular Formula C50H60ClN7O8S4 Molecular Weight 1050
Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE payload 1038/s41589-020-0594-xSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further
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