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Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name CC-92480 Synonyms Mezigdomide

SKU 42719982963
4.2
USD445.00 USD477.00

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Ships within 48 hours · Estimated delivery Aug 20 - Aug 25

Description

Product Name CC-92480 Synonyms Mezigdomide CAS Number 2259648-80-9 Related CAS Molecular Formula C32H30FN5O4 Molecular Weight 567

041 Purity (HPLC) >= 95% Solubility DMSO

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C45H59N11O14 Molecular Weight 978

Product Name CA-Vbn Synonyms Vinylbenzoyl-Halo

Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan macrophage Product Name CC-92480 Synonyms MezigdomideSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU

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