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Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg such as MRI contrast agents

SKU 32769656605
4.5
EUR445.00 EUR478.00

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Description

such as MRI contrast agents

126 Purity (HPLC) >= 95% Solubility DMSO

It acts as a molecular glue for selective degradation of GSPT1

The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg such as MRI contrast agentsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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