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Product Name Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C49H70N8O18 Molecular Weight 1059
especially those targeting lysine side-chain modifications
84 SMILES ClC1=CC(NC(=S)NC2=NC3=C(S2)C=C(C=C3)C#N)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
Product Name Thalidomide-O-PEG1-C2-acid Synonyms Thalidomide-4'-O-PEG1-C2-acid CAS Number n/a Related CAS Molecular Formula C18H18N2O8 Molecular Weight 390
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg Product Name Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
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